Chapter 9 Control and Co-ordination
1. Multiple choice questions
Question 1.
The nervous system of mammals uses both electrical and chemical means to send
signals via neurons. Which part of the neuron receives impulse?
(a) Axon
(b) Dendron
(c) Nodes of Ranvier
(d) Neurilemma
Answer:
(b) Dendron
Question 2.
……………. is a neurotransmitter.
(a) ADH
(b) Acetyl CoA
(c) Acetyl choline
(d) Inositol
Answer:
(c) Acetyl choline
Question 3.
The supporting cells that produce myelin sheath in the PNS are …………….
(a) Oligodendrocytes
(b) Satellite cells
(c) Astrocytes
(d) Schwann cells
Answer:
(d) Schwann cells
Question 4.
A collection of neuron cell bodies located outside the CNS is called …………….
(a) tract
(b) nucleus
(c) nerve
(d) ganglion
Answer:
(d) ganglion
Question 5.
Receptors for protein hormones are located …………….
(a) in cytoplasm
(b) on cell surface
(c) in nucleus
(d) on Golgi complex
Answer:
(b) on cell surface
Question 6.
If parathyroid gland of man Eire removed, the specific result will be …………….
(a) onset of aging
(b) disturbance of Ca++
(c) onset of myxoedema
(d) elevation of blood pressure
Answer:
(b) disturbance of Ca++
Question 7.
Hormone thyroxine, adrenaline and non¬adrenaline are formed from ……………
(a) Glycine
(b) Arginine
(c) Ornithine
(d) Tyrosine
Answer:
(d) Tyrosine
Question 8.
Pheromones are chemical messengers produced by animals and released outside the
body. The odour of these substance affects …………….
(a) skin colour
(b) excretion
(c) digestion
(d) behaviour
Answer:
(d) behaviour
Question 9.
Which one of the following is a set of discrete endocrine gland?
(a) Salivary glands, thyroid, adrenal, ovary
(b) Adrenal, testis, ovary, liver
(c) Pituitary, thyroid, adrenal, thymus
(d) Pituitary, pancreas, adrenal, thymus
Answer:
(c) Pituitary, thyroid, adrenal, thymus
Question 10.
After ovulation, Graafian follicle changes into …………….
(a) corpus luteum
(b) corpus albicans
(c) corpus spongiosum
(d) corpus callosum
Answer:
(a) corpus luteum
Question 11.
Which one of the following pairs correctly matches a hormone with a disease
resulting from its deficiency?
(a) Parathyroid hormone – Diabetes insipidus
(b) Luteinising hormone – Diabetes mellitus
(c) Insulin – Hyperglycaemia
(d) Thyroxine – Tetany
Answer:
(c) Insulin – Hyperglycaemia
Question 12.
……………. is in direct contact of brain in humans.
(a) Cranium
(b) Dura mater
(c) Arachnoid
(d) Pia mater
Answer:
(d) Pia mater
2. Very very short answer questions.
Question 1.
What is the function of red nucleus?
Answer:
Red nucleus plays an important role in controlling posture and muscle tone,
modifying some motor activities and motor coordination.
Question 2.
What is the importance of corpora quadrigemina?
Answer:
Corpora quadrigemina consists of 4 solid rounded structures, viz. superior
and inferior colliculi. Superior colliculi control visual reflexes while
inferior colliculi control auditory reflexes.
Question 3.
What does the cerebellum of brain control?
Answer:
Cerebellum of brain is an important centre which maintains equilibrium of body,
posture, balancing orientation, moderation of voluntary movements and
maintenance of muscle tone.
Question 4.
Name the three ear ossicles.
Answer:
Malleus [hammer], incus [anvil] and stapes [stirrup].
Question 5.
Name the anti abortion hormone.
Answer:
Progesterone.
Question 6.
Name an organ which acts as temporary endocrine gland.
Answer:
Placenta. Corpus luteum in ovary.
Question 7.
Name the type of hormones which bind to the DNA and alter the gene expression.
Answer:
Steroid hormones.
Question 8.
What is the cause of abnormal elongation of long bones of arms and legs and of
lower jaw.
Answer:
Hypersecretion of growth hormones in adults causes abnormal elongation of
long bones of arms and legs and of lower jaw i.e. acromegaly.
Question 9.
Name the hormone secreted by the pineal gland.
Answer:
Melatonin.
Question 10.
Which endocrine gland plays important, role in improving immunity?
Answer:
The endocrine gland, thymus plays an important role in improving immunity.
3. Match the organism with the type of nervous system
found in them.
Answer:
4. Very short answer questions.
Question 1.
Describe the endocrine role of islets of Langerhans.
OR
Islets of Langerhans.
Answer:
Endocrine cells of pancreas form groups of cells called Islets of
Langerhans. There are four kinds of cells in islets of Langerhans which secrete
hormones.
- Alpha
(α) cells : They are 20% and secrete glucagon. Glucagon is a hyperglycemic
hormone. It stimulates liver for glucogenolysis and increases the blood
glucose level.
- Beta
(β) cells : They are 70% and secrete insulin. Insulin is a hypoglycemic
hormone. It stimulates liver and muscles for glycogenesis. This lowers
blood glucose level.
- Delta
(δ) cells : They are 5% and secrete somatostatin. Somatostatin inhibits
the secretion of glucagon and insulin. It also decreases the gastric
secretions, motility and absorption in digestive tract. In general it is a
growth inhibiting factor.
- PP
cells or F cells : They form 5%. They secrete pancreatic polypeptide (PP)
which inhibits the release of pancreatic juice.
Question 2.
Mention the function of testosterone?
Answer:
Testosterone is a steroid sex hormone secreted by testes and cortex of
adrenal glands. It controls the secondary sexual characters in males.
Question 3.
Give symptoms of the disease caused by hyposecretion of ADH.
Answer:
Polydipsia, i.e. frequent thirst and polyuria, i.e. frequent urination are
the symptoms of the disease caused by hyposecretion of ADH.
5. Short answer questions
Question 1.
Rakesh got hurt on his head when he fell down from his motorbike. Which inner
membranes must have protected his brain? What other roles do they have to play
Answer:
- When
Rakesh fell down from his motorbike, the inner membranes that protected
his brain were meninges, viz. dura mater, arachnoid membrane and pia
mater. Morevover, CSF must have also acted as a shock absorber.
- Dura
mater : It is the outer tough membrane protective in function.
- Arachnoid
membrane : It is the middle web-like membrane which communicates with
fluids of upper sub dural space and lower sub arachnoid space.
- Pia
mater : It is the innermost highly vascularised nutritive membrane in
close contact with brain and spinal cord.
Question 2.
Injury to medulla oblongata may prove fatal.
OR
Injury to medulla oblongata causes sudden death. Explain.
Answer:
- Medulla
oblongata is the region of the brain that controls all the involuntary
activities.
- Vital
activities such as heartbeats, respiration, vasomotor activities,
peristalsis, etc. are under the control of medulla oblongata.
- When
medulla oblongata is injured, all these vital functions are instantly
stopped.
- Therefore,
injury to medulla oblongata causes sudden death.
Question 3.
Distinguish between the sympathetic and parasympathetic nervous system on the
basis of the effect they have on:
Heartbeat andUrinary Bladder.
Answer:
Question 4.
While holding a tea cup Mr. Kothari’s hands rattle. Which disorder he may be
suffering from and what is the reason for this?
Answer:
- This
condition is due to Parkinson’s disease.
- It is
due to degeneration of dopamine- producing neurons in the CNS.
- 80%
of the patients develop this condition along with stiffness, difficulty in
walking, balance and coordination.
Question 5.
List the properties of the nerve fibres.
Answer:
- Excitability
/ irritability
- Conductivity
- Stimulus
- Summation
- All or
none
- Refractory
period
- Synaptic
delay
- Synaptic
fatigue
- Velocity.
Question 6.
How does tongue detect the sensation of taste?
Answer:
- The
surface of tongue is with gustatoreceptors.
- These
receptors are sensitive to the chemicals [sweet, salt, sour, bitter and
umami (savory)] present in the food.
- The
receptor cells get stimulated, generate the impulse which is given to the
sensory neuron.
Question 7.
State the site of production and function of Secretin, Gastrin and
Cholecystokinin.
Answer:
Question 8.
An adult patient suffers from low heart rate, low metabolic rate and low body
temperature. He also lacks alertness, intelligence and initiative. What can be
this disease? What can be its cause and cure ?
Answer:
- The
above symptoms indicate that the person is suffering from Myxoedema.
- Myxoedema
is condition caused due to hypothyroidism.
- Hypothyroidism
causes deficiency of thyroid hormones like T3 and T4 (thyroxine).
This results in low BMR.
- This
condition can be cured by giving injections of thyroxine or tablets
containing hormone preparation.
Question 9.
Where is the pituitary gland located? Enlist the hormones secreted by anterior
pituitary.
Answer:
The pituitary gland is attached to hypothalamus on the ventral surface of
brain. It is lodged in a bony depression called sella turcica of sphenoid bone.
For names of hormones:
- GH :
[Growth Hormone/STH : Somatotropic Hormone]
- TSH/TTH
– [Thyroid Stimulating Hormone/ Thyrotropic Hormone]
- ACTH
– [adrenocorticotropic hormone]
- PRL –
[prolactin]
Gonadotropins-
- FSH
[follicle stimulating hormone]
- LH/ICSH
– [leutinizing hormone/ interstitial cells stimulating hormone]
Question 10.
Explain how the adrenal medulla and sympathetic nervous system function as a
closely integrated system.
Answer:
- Adrenal
medulla originates from embryonic neuro – ectoderm.
- It
consists of rounded group of large granular cells called chromaffin cells.
They are modified post-ganglionic cells of sympathetic nervous system
which have lost normal processes and acquired glandular function.
- These
cells are connected with pre-ganglionic fibres of sympathetic nervous
system.
- Hence
adrenal medulla is an extension of sympathetic nervous system.
- Thus
adrenal medulla and sympathetic nervous system functions as a closely
integrated system.
Question 11.
Name the secretion of alpha, beta and delta cells of islets of Langerhans.
Explain their role.
Answer:
Question 12.
Which are the two types of goitre? What are their causes?
Answer:
(1) Goitre is the enlargement of thyroid gland. It is easily visible at the
base of neck when a person is suffering from it.
(2) Goitre is of two types.
- Simple
goitre : It is also called endemic goitre. This is due to iodine
deficiency in the food. This causes iodine deficit in blood. In an attempt
to take more iodine from blood, the blood supply to the gland increases.
This results in swelling on the thyroid.
- Exophthalmic
goitre : It is also called toxic goitre. This is due to hyperactive
thyroid gland. This can happen if there is overstimulation of thyroid due
to excess of ACTH. This disorder is also called Grave’s disease or
hyperthyroidism.
Question 13.
Name the ovarian hormone and give their functions.
Answer:
6. Answer the following.
Complete the table.
Answer:
7. Long answer questions.
Question 1.
Explain the process of conduction of nerve impulses up to development of action
potential.
Answer:
- The
origin and maintenance of resting potential depends on the original state
of no stimulation.
- Any
stimulus or disturbance to the membrane will make the membrane permeable
to Na+ ions. This causes rapid influx of Na+ ions.
- The
voltage gated Na+/K+ channels are unique. They
can change the potential difference of the membrane as per the stimulus
received and also the gates operate separately and are self closing.
- During
resting potential, both gates are closed and resting potential is
maintained.
- However
during depolarization, the Na+ channels open but not the K+ channels.
This causes Na+ to rush into the axon and bring about a
depolarisation. This condition is called action potential.
- Extra
cellular fluid (ECF) becomes electronegative with respect to the inner
membrane which becomes electropositive.
Question 2.
Draw the neat labelled diagrams.
a. Human ear.
Answer:
b. Sectional view of human eye.
Answer:
c. Draw the neat labelled diagram of sagittal section or
L.S. of human brain
Answer:
d. Draw the neat labelled diagram of Multipolar Neuron.
Answer:
Question 3.
Answer the questions after observing the diagram given below.
a. What do the synaptic vesicles contain?
Answer:
Synaptic vesicles contain a neurotransmitter – acetyl choline.
b. What process is used to release the neurotransmitter ?
Answer:
Exocytosis.
c. What should be the reason for the next impulse to be
conducted?
Answer:
Removal of neurotransmitter by the action of acetyl cholinesterase.
d. Will the impulse be carried by post synaptic membrane
even if one pre-synaptic neuron is there?
Answer:
As far as impulse is transmitted by pre-synaptic neuron, it will be received by
post-synaptic neuron.
e. Can you name the channel responsible for their
transmission?
Answer:
Ca++ channel
Question 4.
Explain the Reflex Pathway with the help of a neat labelled diagram.
OR
With the help of a neat and labelled diagram, describe reflex arc.
Answer:
I. Reflex action : Reflex action Is defined as a quick, automatic involuntary
and often unconscious action brought about when the receptors are stimulated by
external or internal stimuli.
II. Reflex arc : Reflex actions are controlled by CNS.
Reflex arc is the structural or functional unit of reflex action. Simple reflex
arc is formed of the following five components.
(1) Receptor organ : The sensory part that receives the stimulus is called
receptor organ. It can be any sense organ that receives the stimulus and
converts it into the impulse, e.g. skin, eye, ear, tongue, nasal epithelium,
etc.
(2) Sensory neuron or afferent neuron:
Sensory part carrying impulse from receptor organ to CNS is called sensory
neuron. Its cyton is located in dorsal root ganglion. Its dendron is long and
connected to receptor while the axon enters in the grey matter of spinal cord
to form a synapse.
(3) Association, adjustor or intermediate neuron : It is
present in the grey matter of spinal cord. Receiving impulse from sensory
neuron, interpreting it and generating motor impulse are done by association
neuron.
(4) Motor neuron (effector) : The cyton of motor neuron is present in the
ventral horn of grey matter and axon travels through ventral root. It conducts
motor impulse from spinal cord to effector organ.
(5) Effector organ : Effector organ is a specialized part of
the body which is excited by receiving the motor impulse. It gives proper
response to the stimulus, e.g. muscles or glands. The path of reflex action is
followed by the unidirectional impulse. It originates in the receptor organ and
ends in effector organ through CNS.
Question 5.
Krishna was going to school and on the way he saw a major bus accident. His
heartbeat increased and hands and feet become cold. Name the part of the
nervous system that had a role to play in this reaction.
Answer:
- The
symptoms observed in Krishna were due to sympathetic nervous system.
Emergency conditions trigger sympathetic nervous system to stimulate
adrenal medulla.
- The
cells of adrenal medulla secrete catecholamines like adrenaline and
nor¬adrenaline.
- These
hormones have direct effect on the pacemaker of the heart which causes
increase in the heart rate and other associated symptoms.
- This
is a typical fright reaction caused by intervention of sympathetic nervous
system.
Question 6.
What will be the effect of thyroid gland atrophy on the human body?
Answer:
- Atrophy
means degeneration. Atrophy of thyroid gland will result in deficient
secretion of thyroid hormones leading to hypothyroidism. Deficiency of
thyroid hormones [T3 and T4] and
thyrocalcitonin will cause following effects on the body.
- Decrease
in BMR i.e. basal metabolic rate, decrease in the blood pressure, heart
beat, body temperature, etc.
- Occurrence
of myxoedema in which there is abnormal deposition of fats under the skin
giving puffy appearance in adults.
- Irregularities
in menstrual cycle in case of female patients.
- Hair
become brittle and fall.
- Calcium
metabolism also disturbs due to lack of thyrocalcitonin.
Question 7.
Write the names of hormones and the glands secreting them for the regulation of
following functions
(a) Growth of thyroid and secretion of thyroxine.
Answer:
TSH by adenohypophysis.
(b) Helps in relaxing pubic ligaments to facilitate easy
birth of young ones.
Answer:
Relaxin by degenerating corpus luteum of the ovary.
(c) Stimulate intestinal glands to secrete intestinal
juice.
Answer:
Secretin by duodenal mucosa.
(d) Controls calcium level in the blood.
Answer:
Calcitonin [hypocalcemic hormone] by thyroid and parathormone [
hypercalcemic hormone] by parathyroid glands.
(e) Controls tubular absorption of water in kidneys.
Answer:
ADH by hypothalamus.
(f) Urinary elimination of water.
Answer:
Atrial natriuretic factor by atria of heart.
(g) Sodium and potassium ion metabolism.
Answer:
Aldosterone by adrenal cortex.
(h) Basal Metabolic rate.
Answer:
T3 and T4 by thyroid gland.
(I) Uterine contraction.
Answer:
Oxytocin by hypothalamus.
(j) Heartbeat and blood pressure.
Answer:
Adrenaline, non-adrenaline [stimulation] and acetylcholine [inhibition] by
adrenal medulla.
(k) Secretion of growth hormone.
Answer:
GHRF by hypothalamus.
(l) Maturation of Graafian follicle.
Answer:
FSH by anterior pituitary.
Question 8.
Explain the role of hypothalamus and pituitary as a coordinated unit in
maintaining homeostasis.
Answer:
- Homeostasis
is maintenance of constant internal environment of the body.
- When
certain hormones from any endocrine glands are secreted in excess
quantity, the : inhibiting factors from hypothalamus, automatically exert
negative feedback and stop the production of stimulating hormones from
pituitary.
- Similarly,
if any hormone is in deficit, then j the concerned gland is given message
through releasing factor. This way the hormone production remains in a
balanced state or homeostasis.
- E.g.
If thyroxine from thyroid gland is secreted in excess, the secretion of
TSH from pituitary is stopped by stopping the production of TRF from
hypothalamus.
- Though
most of the endocrine glands are under the influence of pituitary gland,
it is in turn controlled by hypothalamus.
- Hypothalamus
secretes releasing factors and inhibiting factors and hence regulate the
secretions of pituitary (hypophysis).
- There
is negative feedback mechanism in controlling the secretions of the
endocrine glands.
- Hypothalamus
forms the hypothalamo- hypophyseal axis through which transportation of
neurohormones take place.
Following are the releasing and inhibiting factors produced
by hypothalamus:
- Somatotropin/GHRF
: It stimulates release of growth hormone.
- Somatostatin/GHRIF
: It inhibits the release of growth hormone.
- Adrenocorticotropin
Releasing Hormone / CRF : It stimulates the release of ACTH by the
anterior pituitary gland.
- Thyrotropin
Releasing Hormone /TRF : It stimulates the release of TSH by anterior
pituitary gland.
- Gonadotropin
Releasing Hormone (GnRH) : It stimulates pituitary to secrete
gonadotropins.
- Prolactin
Inhibiting Hormone (Prolactostatin) : It inhibits prolactin released by
anterior pituitary gland.
- Gastrin
Releasing Peptide (GRP).
- Gastric
Inhibitory Polypeptide (GIP).
Question 9.
What is adenohypophysis ? Name the hormones secreted by it.
Answer:
- Adenohypophysis
is the large anterior lobe of pituitary gland.
- It is
derived from embryonic ectoderm in the form of Rathke’s pouch which is a
small outgrowth from the roof of embryonic stomodaeum.
- It is
made up of epitheloid secretory cells.
It secretes following hormones:
- GH :
[Growth Hormone/STH : Somatotropic Hormone]
- TSH/TTH
– [Thyroid Stimulating Hormone/ Thyrotropic Hormone]
- ACTH
– [adrenocorticotropic hormone]
- PRL –
[prolactin]
Gonadotropins-
- FSH
[follicle stimulating hormone]
- LH/ICSH
– [leutinizing hormone/ interstitial cells stimulating hormone]
Question 10.
Describe, in brief, an account of disorders of adrenal gland.
Answer:
(1) Disorders of adrenal cortical secretions are caused due to
hyposecretion and hypersecretion of adrenal corcoid hormones.
(2) Hyposecretion of corticosteroids causes Addison’s
disease.
(3) The symptoms of Addison’s disease are low blood sugar,
low body temperature, feeble heart action, low BR acidosis, low Na+ and
K+ concentration in plasma, excessive loss of Na+ and
water in urine, impaired kidney functioning and kidney failure, etc. it leads
to weight loss, general weakness, nausea, vomiting and diarrhoea.
(4) Hypersecretion of corticoids causes Cushing’s disease.
(5) The symptoms of Cushing’s disease are high blood sugar
level, glucosuria, alkalosis, enhancement of total quantity of electrolytes in
extracellular fluid, polydipsia, increased BR muscle paralysis, obesity,
wasting of limb muscles, etc.
Question 11.
Explain action of steroid hormones and proteinous hormones.
OR
Explain the mode of action of steroid hormones.
Answer:
The hormones always act on their target organs or tissues to induce their
effects. The target tissues have specific binding sites or receptor sites which
contain hormone receptors.
I. Steroid hormones:
- The
steroid hormones are lipid soluble and can easily cross the lipoproteinous
plasma membrane.
- The
hormone receptors for steroid hormones are present in cytoplasm or in
nucleus.
- Hormone-receptor
complex formed in cytoplasm enters the nucleus and regulate the gene
expression or chromosome function.
- In
some cases the receptors are present inside the nucleus where hormone
receptor complex is formed.
- These
complexes interact with the genome to evoke biochemical changes that
result in physiological and developmental functions.
II. Protein hormones:
- The
hormone receptors for protein hormones are present on the cell membrane
(i.e. membrane bound receptors).
- When
the hormone binds to its receptor, it forms hormone-receptor complex. Each
receptor is specific to a specific hormone.
- The
hormones which interact with membrane bound receptors normally do not
enter the target cell but generate second messengers. Such as cyclic AMP
Ca++ or IP (Inositol triphosphate), etc.
- This
leads to certain biochemical changes : in the target tissue.
- Thus,
the tissue metabolism and consequently the physiological functions are
regulated by hormones.
Question 12.
Describe in brief an account of disorders of the thyroid.
OR
What are the functional disorders of thyroid gland? Describe in brief.
Answer:
Disorders of thyroid gland are of three types, viz. hypothyroidism,
hyperthyroidism and simple goitre.
(1) Hypothyroidism : Hypothyroidism is deficient secretion of thyroxine. This
hyposecretion causes two types of disorders, viz. cretinism in children and
myoxedema in adults.
(i) Cretinism : Hyposecretion of thyroxine in childhood causes cretinism. The
symptoms of cretinism are retardation of physical and mental growth.
(ii) Myxoedema : Deficiency of thyroxine in adults causes
this disorder. It is also referred to as Gull’s disease. Symptoms are
thickening and puffiness of the skin and subcutaneous tissue particularly of
face and extremities. Patients with low BMR. It also causes mental dullness,
loss of memory, slow action.
(2) Hyperthyroidism : Excessive secretion of thyroxine
causes exophthalmic goitre or Grave’s disease. There is slight enlargement of
thyroid gland. It increases BMR, heart rate, pulse rate and BE Reduction in
body weight due to rapid oxidation, nervousness, irritability. Peculiar symptom
is exophthalmos, i.e. bulging of eyeballs with staring look and less blinking.
This is caused by deposition of fats behind the eye balls in eye sockets. There
is muscular weakness and loss of weight.
(3) Simple goitre (Iodine deficiency goitre) : Simple goitre
occurs due to deficiency of iodine in diet or drinking water. Simple goitre
causes enlargement of thyroid gland. Thyroid gland in an attempt to get more
iodine from the blood, swells due to increased blood supply. Prevention of
goitre can be done by administering iodized table salt. It is also called
endemic goitre as it is common in hilly areas.